Production of Biotechnology Based Bulk Drugs
Biotechnology is the use of living systems and organisms to develop or make products, or “any technological application that uses biological systems, living organisms, or derivatives thereof, to make or modify products or processes for specific use” (UN Convention on Biological Diversity, Depending on the tools and applications, it often overlaps with the (related) fields of bioengineering, biomedical engineering, bio manufacturing, molecular engineering, etc.
Biotechnology also utilizes these products for manufacturing purpose. Some of the examples of drugs produced through biotechnology are penicillin, lincomycin, streptomucin, tylosin, peptide antibiotics, cephalosporins, etc. Modern use of similar terms includes genetic engineering as well as cell and tissue culture technologies. Biotechnology draws on the pure biological sciences and in many instances is also dependent on knowledge and methods from outside the sphere of biology. Conversely, modern biological sciences are intimately entwined and dependent on the methods developed through biotechnology and what is commonly thought of as the life sciences industry.
The present book contains process of biotechnology based bulk drugs like penicillin, B lactam antibiotics, aminoglycoside antibiotics, peptide antibiotics, anti-cancer agents, lincomycin etc. This is very resourceful book for entrepreneurs, technocrats, research scholars, libraries etc.
Market outlook
The global medical industry is going to experience tremendous growth in the coming years with a range of development and investment opportunities for companies looking out to enter in this industry or to expand within. Healthcare industry is one of the largest sectors in the country both in terms of revenue as well as employment.
The global bulk drugs market was valued at around USD122 b in 2014 and is expected to reach USD175 b by 2019, growing at a CAGR of 7.5% during 2014–19.
India’s bulk drug exports are likely to grow at a compounded annual growth rate (CAGR) of 12-14 per cent till 2018-19, driven largely by exports to regulated markets as well as continued growth in the semi-regulated markets.
Driven by exports to both regulated and semi-regulated markets, India’s bulk drug exports are likely to grow at a compound annual growth rate (CAGR) of 12–14% up to 2018–2019.
Most of this growth is expected to come from generics, with exports of bulk drugs used for manufacturing off-patent drugs expected to continue to grow at a 12–14% CAGR in the next five years till 2018–2019. Demand for active pharmaceutical ingredients from on-patent drugs, on the other hand, is expected to grow at a slower pace.
Global Drug Market
| 2012-13 | 2016-17 | %Growth | |
| Global pharma market (in $ bn) | 962 | 1200 | 24.7% |
| Global generic market (in $ bn) | 274 | 432 | 57.7% |
| Global generic market (in $ bn) | 28.5% | 36% | |
| 2012-13 | 2014-15 | %Growth | |
| Indian pharma generic drug exports (in $ bn) | 15 | 25 | 66.7% |
The generic drug market is expected to grow at nearly at 60 percent by the year 2016-2017 and contribute nearly 36 percent of the total market in the year 2016-2017.
The Indian pharmaceuticals market increased at a CAGR of 17.46 per cent in 2015 from USD6 billion in 2005 and is expected to expand at a CAGR of 15.92 per cent to USD55 billion by 2020.
Growing per capita sales of pharmaceuticals in India offers ample opportunities for players in this market Per capita sales of pharmaceuticals is expected to expand at a CAGR of 19.4 per cent to USD33 by 2016.
The Indian pharmaceuticals market increased at a CAGR of 17.46 per cent during 2005-16 with the market increasing from US$ 6 billion in 2005 to US$ 36.7 billion in 2016 and is expected to expand at a CAGR of 15.92 per cent to US$ 55 billion by 2020.
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