The anti-inflammatory enzyme bromelain, which comes from the pineapple plant, has become one of the most popular supplements on the market right now. Despite being discovered in the 1800s, it wasn’t until the 1980s when its commercial production started to rise and its therapeutic capabilities were uncovered by researchers that the full potential of this enzyme became clear.
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Uses and applications of Bromelain
There are several uses for bromelain stem in the medical, industrial, and other fields. Bromelain is one of the chemicals that is generally regarded as safe according to the Food and Drug Administration of the USA (Food and Drug administration, 2006). It is widely utilized in the food sector for things like meat tenderization, baking procedures, the creation of protein hydrolysates, beer clarification, as a dietary supplement, and the prevention of apple juice browning. Additionally, it is utilized as an active component in the cosmetic industry to deliver mild peeling effects. Additionally, it has been applied to the leather industry’s pre-tanning, softening, and batting of skin (Walsh, 2002). In the textile industry, bromelain is used to break down or partially dissolve protein fibre from silk and wool, increasing the dyeing qualities of those fibres. It has been documented that bromelain can hydrolyze the insoluble proteins in leather jackets to release antimicrobial peptides.
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Bromelain has further medical uses, such as reducing the growth of tumours, treating third-degree burns, and enhancing the effectiveness of antibiotics. Additionally, it is employed as a medication for the systemic oral management of inflammatory, blood coagulation-related, and occasionally malignant disorders. Additionally, bromelain helps increase drug absorption, particularly for antibiotics, and is implicated in the reversible inhibition of platelet aggregation, sinusitis, bronchitis, angina pectoris, thrombophlebitis, surgical traumas, and pyelonephritis (Maurer, 2001). In many cases of intestinal problems, bromelain has also been utilized successfully as a digesting enzyme. It has been demonstrated that in the event of a deficiency, the enzyme serves as a suitable alternative for trypsin and pepsin. Additionally, it treats stomach ulcers in test animals. Recently, it was revealed that bromelain increased the healing of gunshot wounds and improved the wound microenvironment.
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Extraction of Bromelain
In order to get rid of the remnants of the culture, the plants are washed under running water. They are then put through a first extraction and run through a filter press to produce a juice that contains between 60 and 80 percent bromelain and is stored at 0 to 5 °C.
The resultant pulp, which naturally includes bromelain, is dissolved at a concentration of between 0.03 and 0.2 M, at a pH range of between 5.3 and 7.2, in an extraction buffer containing cold (0-5 ° C) potassium phosphate (K2PO4) to prevent denaturalization of the enzyme.
After allowing it to rest for 20 to 30 minutes, the mixture is run through a filter press to obtain a second extraction juice; the first juice and the second juice are then combined at 2000 to 5000 rpm for one to two minutes. Next, the mixture is centrifuged at 5000–10,000 rpm for 15-20 minutes at 0–4 °C to remove precipitate and recover the supernatant, which is then preserved at –80 to –2 °C. Finally, the extract is lyophilized for which said extract should contain at least 10-15% of solids.
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Indian Market Outlook
The fast expanding bromelain import market in India appears to be a positive indicator for domestic production. India purchased bromelain worth over $2 million in 2014 from nations like China, Peru, Brazil, and France. According to estimates, the Indian government intends to extend the area planted with pineapples by up to 10% in 2018, with a goal of producing 100,000 tons by 2020. India might benefit from this and rise to the top of the world exporters and producers. In recent years, demand for bromelain, an anti-inflammatory enzyme typically extracted from the pineapple plant (Ananas comosus), has increased by a factor of three in India.
Indian consumers are spending more on imports as they become more aware of the therapeutic advantages of bromelain and acknowledge the global research demonstrating its promise as a painkiller and a possible defence against cancer and heart disease.
Increased sales are also a result of new product diversification and price discrimination. Due to its medical qualities, bromelain is frequently employed in food products, nutraceuticals, and pharmaceuticals. Therefore, if Indians continue to buy things made in their country, the trend will continue.
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Global Market Outlook
By 2030, it is anticipated that the global bromelain market would be worth USD 45.09 million. From 2022 to 2030, a CAGR of 7.1% is anticipated. Due to the product’s multiple health advantages, the healthcare, pharmaceutical, and dietary supplement businesses are increasingly incorporating it into their products, which is a major factor in the market expansion.
A CAGR of 7.4% in terms of revenue is predicted for the application area for dietary supplements between 2022 and 2030. This is ascribed to rising public knowledge of nutritional supplements and self-care, as well as to rising consumer spending power.
From 2022 to 2030, the healthcare application segment is anticipated to have revenue growth at a CAGR of 7.3%. This is because bromelain is used in many medications for treating illnesses like cancer, rheumatoid arthritis, and HIV. Due to its natural origins, bromelain has no or few negative effects, which helps drive the segment’s expansion.
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As a key supplier of bromelain, the Asia Pacific area is predicted to see an exponential CAGR of 7.9% in terms of revenue from 2022 to 2030. The broader regional market is expanding as a result of the people’s greater purchasing power brought on by economic expansion.
Because of unexplored market prospects and rising purchasing power due to the region’s developing economies, the Central & South America region is predicted to experience a rapid CAGR of 7.5% in terms of revenue from 2020 to 2030.
Hong Mao Biochemicals Co., Ltd., Enzybel International SA, and the Great Food Group of Companies are major players that dominate the sector.
Niir Project Consultancy Services (NPCS) prepares multiple project reports on different segment one of the project report by NPCS is Bromelain from Pineapple – Detailed Project Report, Profile, Business Plan, Industry Trends, Market Research, Survey, Machinery, Raw Materials, Feasibility Study and Investment Opportunities. The detailed project report by NPCS covers all the important aspects of a business from analyzing the market, confirming availability of various necessities such as plant & machinery, raw materials to forecasting the financial requirements. The project reports are not only used in India but worldwide by engineers, project consultants & industrial consultancy firms. You can get the project reports from the official site of NPCS.
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